mrm-performance-kit

MRM Proteomics’ PeptiQuant™ LC-MS Platform Performance Quality Control Kit for Targeted Quantitative Proteomics allows users to test the effectiveness of their LC-MS platform before conducting MRM-MS analyses.

 

The PeptiQuant™ LC-MS Platform Performance Kit for quantitative plasma proteomics is available in
two formats:

 

• Daily Use Format
• Comprehensive Monthly Use Format

 

In using the supplied kit, users can compare their quantitative results (in terms of precision, limit of quantitation, protein concentration, etc.) to the “known” values for the proteins in the reference kit for performance evaluation.  Doing so will highlight the presence of instrument-specific issues that will need to be addressed prior to performing the users quantitative proteomics research of interest.

 

The LC-MS Platform Performance Kit is available for a multiple chromatographic systems from standard- to nano-flow and for a range of mass spectrometers from different vendors.

 

Daily Use Format

MRM Proteomics’ Daily Use PeptiQuant™ LC-MS Platform Performance Kit for quantitative plasma proteomics contains a plasma tryptic digest that has been spiked with a balanced stable isotope-labeled standard (SIS) peptide mixture.  The supplied standard is lyophilized and ready for LC-MRM/MS analysis upon rehydration.  This kit is designed to evaluate the performance of the LC-MS platform on a daily basis.

 

In using the supplied kit, users can compare their quantitative results (in terms of precision, limit of quantitation, protein concentration, etc.) to the “known” values for the proteins in the reference kit for performance evaluation.  Doing so will highlight the presence of instrument-specific issues that will need to be addressed prior to performing the users quantitative proteomics research of interest.

 

Comprehensive Monthly Use Format

MRM Proteomics’ Monthly Use PeptiQuant™ LC-MS Platform Performance Kit for quantitative plasma proteomics contains 7 samples of a plasma tryptic digest that have been spiked with a 10,000-fold concentration range of a balanced stable isotope-labeled standard (SIS) peptide mixture.  The supplied standards are lyophilized and ready for LC-MRM/MS analysis upon rehydration.  This kit is designed to evaluate the performance of the LC-MS platform.

 

In using the supplied kit, users can compare their quantitative results (in terms of precision, limit of quantitation, protein concentration, etc.) to the “known” values for the proteins in the reference kit for performance evaluation.  Doing so will highlight the presence of instrument-specific issues that will need to be addressed prior to performing the users quantitative proteomics research of interest.

 

It is suggested that the 7 standard samples in the Monthly Use PeptiQuant™ LC-MS Platform Performance Kit be analyzed in quintuplicate on a monthly basis for comprehensive quality control (QC) assessment.

 

Order a Kit

 

MRM Proteomics – Protein Quantification and Biomarker Discovery by Multiple Reaction Monitoring