PeptiQuant™ Services

Expert Protein Quantitation
by MRM-MS

MRM Proteomics offers sample analysis using our high quality PeptiQuant™ Plus technology to quantify up to 375 proteins from a single sample.

Our PeptiQuant™ Plus assays employ a rigorous MRM-MS quantitation strategy that uses paired heavy/light peptide standards. The unlabeled “light” peptide mix is used to create the calibration curve and the “heavy”’ SIS peptide mix, spiked into every sample/standard at a fixed concentration, is used as a normalizer. Our methodology ensures robust and precise measurements, even at low concentrations.

Applications

Features

  • Highly multiplexed panels for accurate quantitation of 100s of proteins from a single sample

  • High purity paired heavy/light peptide standards for precise quantitation of every targeted protein

  • Quality MRM-MS technology you can trust: all assays are highly reproducible, rigorously tested for interferences, and characterized according to Tier II CPTAC guidelines

  • Panels include medium-low abundance proteins associated with cancer, CVD, and other diseases

  • Compatible with a variety of sample types

  • Minimal sample volume (25-100 uL)

  • Analyses are suited for a variety of complex matrices (plasma, CSF, urine, etc.)

  • Extremely high specificity (not possible with antibody-based methods)

  • Discrimination of protein isoforms

  • Depletion or enrichment not required

  • No antibodies required